ColombiaColombia
Primera APrimera A
Round 12

Santa Fe vs Deportivo Cali Prediction & Betting Tips

23 Sept 2026
0-1
Full Time
Estadio El Campin, Bogota
Correct
Our #1 Pick
Total Goals
Under 2.5
0 : 1
FT

Betting Tips

45%
27%
27%
Santa FeDrawDeportivo Cali
Match Result
Santa Fe
45%
Total Goals
Under 2.5
59%
Both Teams Score
No
53%
Double Chance
Home/Draw
37%
Asian Handicap
AH Home -0.50
@ 2.01
50%
Odds updated hourly from bookmakers
Predictions recalculated every 2 hours
Locked 2 hours before kickoff

Expert Analysis

Alexey Andrianov
Alexey Andrianov Founder & Lead Analyst
60.3% 30+ yrs
12 min read

Two clubs separated by a single point and three positions in the Clausura standings prepare to meet at Estadio El Campin on Wednesday, with Santa Fe holding the clearer sense of purpose heading into this pivotal encounter. The capital side sits sixth with 16 points and carries genuine aspiration tow...

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Match Facts

Santa Fe
Santa Fe score 50% of their goals after the 75th minute (3 goals)
Santa Fe average 3 yellow cards per game (15 in 5 matches)
Deportivo Cali
Deportivo Cali have kept 3 consecutive clean sheets
Deportivo Cali win 67% at home but just 0% away — a stark contrast
Deportivo Cali average 3.3 yellow cards per game (20 in 6 matches)
S. Rodríguez has scored 3 of Deportivo Cali's 9 goals (33%)
Deportivo Cali failed to score in 2 of 6 matches (33%)

Key Statistics

Santa Fe7
6Draws
7Deportivo Cali
2.2Avg Goals
45%BTTS
35%Over 2.5
23 Sept 2026Santa Fe0-1Deportivo Cali
19 Mar 2026Deportivo Cali1-1Santa Fe
10 Nov 2025Santa Fe1-0Deportivo Cali
17 May 2025Deportivo Cali0-2Santa Fe
21 Aug 2024Deportivo Cali1-3Santa Fe
View all H2H matches

Full Match Analysis

Alexey Andrianov
Alexey Andrianov ✓
Founder & Lead Analyst
60.3% Our Pick Win Rate
30+ Years Experience
16.2k Predictions Tracked
Santa Fe vs Deportivo Cali — match prediction & preview
Santa Fe
LWWLW
Recent formvs
Deportivo Cali
WWDDW

Santa Fe Seek to Capitalize on Motivation Edge Against In-Form Deportivo Cali

Two clubs separated by a single point and three positions in the Clausura standings prepare to meet at Estadio El Campin on Wednesday, with Santa Fe holding the clearer sense of purpose heading into this pivotal encounter. The capital side sits sixth with 16 points and carries genuine aspiration toward a qualification berth, a goal reflected in their unbeaten run of five matches stretching back through their recent form. Their visitors from Cali arrive in eighth place on 15 points, with three wins from their last four games masking the disappointment of a recent defeat that halted their momentum.

The stylistic contrast between these Colombian rivals promises a fascinating tactical chess match. Santa Fe, buoyed by their qualification chase, will look to impose their rhythm early against a Deportivo Cali side that has proven capable of punishing complacency. The odds on Bet365 reflect the closeness of this contest, with Santa Fe priced at 2.15, the draw at 3.2, and Deportivo Cali at 3.5, suggesting neither side holds a decisive advantage on paper. With three days of rest for both outfits and everything to play for in theBogota night air, this Clausura Round 12 fixture carries weight beyond mere league positions.

Key Players and Probable Lineups

When these two Colombian clubs meet, all eyes will be on the attacking threats that could decide the outcome. For Santa Fe, the attacking burden falls heavily on C. Mafla, who has found the net twice this campaign alongside N. Bustos, whose creative influence with two assists has been crucial in unlocking opposition defenses. The combination of goal-scoring prowess and playmaking ability gives Santa Fe a multifaceted front line capable of adapting to different game situations. Defensively, E. Olivera brings stability at the back while also contributing to the attack when opportunities arise.

Deportivo Cali's most dangerous weapon this season has been S. Rodríguez, whose three goals make him the joint top scorer across both squads in this fixture context. His clinical finishing ability will be pivotal if Cali are to breach Santa Fe's defense. Supporting him, J. Martínez has been instrumental in chance creation with three assists, forming a productive partnership that stretches opposing backlines. A. Hurtado adds another goalscoring option, ensuring Deportivo Cali possess multiple routes to goal.

Santa Fe are expected to set up in a 4-2-3-1 formation with A. Mosquera anchoring the defense behind H. Palacios and E. Olivera, while C. Mafla operates as an attacking outlet alongside V. Moreno and L. Palacios in midfield. The creative hub revolves around E. Mosquera and A. Zapata, with H. Rodallega leading the line as the lone striker. For Deportivo Cali, the projected 4-4-2 features P. Gallese in goal, protected by Fernando Antonio Álvarez Amador and F. Aguilar at center-back, with A. Correa and F. Viáfara stationed on the flanks. The midfield quartet of A. Colorado, E. Reynoso, Y. Quintero, and D. Giraldo will look to control tempo, supporting the strike pairing of J. Martínez and J. Dinenno. These projected lineups are based on appearances this season and remain subject to final confirmation from the coaching staff.

Contrasting Shapes and Tempo: How Santa Fe's Control Meets Cali's Threatening Width

The fixture at Estadio El Campin pitches two sides with distinctly different structural philosophies into what promises to be a tightly contested encounter. Santa Fe operate from a 4-2-3-1 formation, a setup that prioritizes control through midfield dominance and vertical transitions through the number ten position. The twin pivot of two deep-lying midfielders provides defensive screening while allowing the attacking trio ahead to press aggressively and exploit space in behind opposition lines. This structured approach has delivered just six goals across nine Clausura matches, yet only five conceded speaks to a disciplined defensive record that keeps them firmly in qualification contention.

Deportivo Cali, meanwhile, line up in a traditional 4-4-2 that places greater emphasis on defensive solidity across the midfield band and directness in the final third. Their 4-4-2 shape is designed to be compact when defending and expansive when transitioning, with wide midfielders tucking inside to create numerical advantages centrally while also stretching play when possession allows. The two-striker partnership provides a constant aerial and hold-up threat, and Cali's nine goals from nine matches suggests they carry more immediate firepower than their hosts. Notably, Cali's most productive scoring window falls in the 61-75 minute bracket, suggesting they build momentum through the middle stages of matches rather than chasing late results.

Santa Fe's greatest threat materializes in the opposite window—the 76-90 minute period accounts for half of their entire goal tally, indicating a side built to impose themselves physically as opponents tire. With Bet365 pricing Santa Fe at 2.15 to win, the bookmakers recognize their home advantage and structural solidity, though the narrow margins in a fixture between sixth and eighth place are reflected in those odds. Cali's two clean sheets this Clausura provides a platform for an organized defensive display, but their four-game unbeaten run before the recent loss to... suggests they arrive in confident mood. The key tactical battle will centre on whether Santa Fe can suffocate Cali's central channels through their double pivot, or whether Cali's superior goal threat and recent form can expose the hosts' relatively modest attacking output. With both sides sharing identical rest periods, freshness should not prove a differentiating factor—what will matter is execution of contrasting game plans in a match where small margins define the outcome.

Santa Fe and Deportivo Cali Head Into Crucial Clausura Clash in Tight League Battle

Both Santa Fe and Deportivo Cali arrive at this Clausura 12 fixture in solid but distinctly different form, setting up an intriguing contest between two sides separated by just a single point in the Primera A standings. Santa Fe occupy sixth place with 16 points and carry a four-match unbeaten sequence into this encounter, a run that includes victories over top-tier opponents and an impressive derby triumph. Their recent sequence of WWDWD demonstrates consistency, though two of their last five matches have ended in draws, highlighting a tendency to drop points against more defensive setups.

Their most recent outing saw them claim a commanding 4-1 victory away to Alianza Valledupar, showcasing their attacking potential after earlier recording a narrow 1-0 home win against Deportes Tolima. Those results sandwich a 2-2 draw with Fortaleza FC and a thrilling 3-2 derby victory over Millonarios, indicating Santa Fe can both score freely and be vulnerable at the back. Their average of 1.7 goals scored per game ranks among the stronger attacking records in the division, while their clean sheet percentage of 40% suggests defensive frailties that this opponent might exploit. Notably, 60% of their matches have featured both teams scoring, reflecting their tendency to contribute to open contests.

Deportivo Cali sit eighth on 15 points and enter this fixture having suffered just one defeat across their last five matches. Their WWDDL sequence includes back-to-back wins before consecutive draws, with their sole reversal coming in a 1-2 away loss to Atletico Nacional. That defeat to Nacional represents their toughest test of recent weeks, and they responded well to that setback by defeating Cucuta 3-0 at home and earning a creditable 2-1 away win at Once Caldas. Their more recent draws against Millonarios and Bucaramanga both on the road demonstrate resilience in difficult environments, suggesting they possess the character to compete in what promises to be a hostile atmosphere at Estadio El Campin.

When examining the statistical comparison, Santa Fe hold advantages in overall form, attack, and defensive metrics according to the available data. Their superior scoring average of 1.7 compared to Cali's 1.5, combined with a higher clean sheet percentage, paints Santa Fe as the more complete outfit on current evidence. However, Cali's slightly superior defensive record in terms of goals conceded per game (0.9 versus 1.0) indicates they cannot be easily broken down. Both teams show identical BTTS percentages of 60%, suggesting bettors should anticipate goals at both ends. The weight of recent history tilts toward Santa Fe given their extended unbeaten run and superior head-to-head form figures, but Cali's away resilience and ability to grind out results make them a dangerous opponent capable of troubling even in-form sides.

Santa Fe's Recent Dominance in the Clásico Bogotano

The head-to-head record between Santa Fe and Deportivo Cali reveals a closely contested rivalry over 19 meetings, with Santa Fe holding a marginal advantage through seven victories compared to Cali's six, while six encounters have ended in draws. This equilibrium in the overall record underscores the competitive nature of the fixture, suggesting neither side has established clear psychological superiority across the full span of their matchups.

However, the recent meetings tell a markedly different story. Santa Fe have secured four wins in their last five encounters against Deportivo Cali, including a 3-1 victory in August 2024, a 2-0 away win in May 2025, a narrow 1-0 triumph in November 2025, and another 1-0 home win in February 2024. The only deviation from this dominance came in their most recent clash in March 2026, which ended in a 1-1 stalemate. This pattern suggests Santa Fe have found a tactical approach that consistently troubles Deportivo Cali, particularly in games played at Santa Fe's home ground.

From a betting perspective, the data presents mixed signals. The average goals per meeting stands at 2.26, indicating generally low-scoring affairs, while both teams have found the net in 47% of their encounters. Given the recent trend of Santa Fe victories and the likelihood of a tight contest, the historical goal average and BTTS rate suggest cautious optimism for those considering the Under 2.5 goals market or the draw outcome, particularly if Santa Fe's defensive solidity continues to negate Cali's attacking threat.

Why Santa Fe Holds the Edge at Estadio El Campin

The Colombian Clausura reaches round 12 with a compelling mid-table clash as Santa Fe play host to Deportivo Cali at Estadio El Campin in Bogota. The hosts occupy sixth position with 16 points from four wins, four draws and a single defeat, while their visitors from Cali sit just below in eighth place with 15 points, having recorded four victories, three draws and two losses. The proximity in the standings makes this a fascinating tactical battle where the outcome could significantly reshape both teams' trajectories in the closing stages of the tournament. Santa Fe's superior defensive record, conceding just one loss, suggests they arrive with a solid foundation, though Deportivo Cali's marginally better attacking output provides them with a genuine threat on their travels.

Examining the 1X2 odds, the market positions Santa Fe as narrow favourites with the best available price of 2.18 at Betano, translating to an implied probability of 42.8 percent for a home victory. The draw is priced around 2.9 by most bookmakers, though punters seeking the best value can find 3.2 at Bet365, representing reasonable value given the tight nature of this fixture. Deportivo Cali's away success is considered the least likely outcome at 3.6 across most platforms, with Pinnacle offering the most competitive line at 3.65. Our prediction leans toward a Santa Fe win with 45 percent confidence, a selection backed by their unbeaten record at home this campaign and the psychological advantage of playing at altitude in Bogota, where visiting teams historically struggle to impose their rhythm.

The under 2.5 goals market presents the strongest conviction in our analysis at 60 percent confidence, reflecting the defensive solidity both clubs demonstrate. Santa Fe have proven difficult to break down throughout the Clausura, while Deportivo Cali have shown a tendency to tighten their shape away from home rather than commit numbers forward. The BTTS selection of no at 54 percent confidence aligns with this pattern, suggesting clean sheets remain likely for at least one side. For punters seeking additional security, the double chance 1X at 37 percent confidence provides insurance against a potential upset, though the primary selection of a Santa Fe victory represents the value play given their current form and home advantage at this crucial stage of the season.

Secondary Markets: Where Value Lies in Santa Fe vs Deportivo Cali

While the outright result presents a closely contested affair between two sides separated by just one point in the Primera A standings, the statistical model identifies several secondary angles worth exploring for the encounter at Estadio El Campin. The half-time market shows the strongest conviction in the portfolio, with a draw at the break valued at odds of 1.88 and backed by a 46% confidence rating. Given both teams' recent form and the positioning of Santa Fe in sixth place with sixteen points and Deportivo Cali in eighth with fifteen, a tight opening forty-five minutes appears likely, reflecting the competitive balance between these Colombian giants.

The correct score projection offers more substantial returns for those seeking longer odds, with a 1:0 result carrying odds of 5.60 and the highest confidence level at 18% among goal-based markets. This narrow margin aligns with both teams' defensive solidity and suggests that a single goal could prove decisive. The corners market presents the most statistically confident play, with under 9.5 corners priced at 1.55 and carrying a 58% confidence rating, indicating that the match flow may be more structured than expansive. For goal-scorer punts, Hugo Rodallega emerges as the standout anytime selection at odds of 2.50 with 40% confidence, representing a player capable of making the difference in a low-scoring affair.

Santa Fe's Home Strength Makes Them the Safer Pick at El Campín

The weight of evidence points toward Santa Fe avoiding defeat in this Clausura 12 encounter at Estadio El Campín. With four wins from nine matches and ten of their sixteen points earned on home soil, Santa Fe have demonstrated the kind of home consistency that separates them from Deportivo Cali. The visitors arrive in eighth place with two losses already on their travels this campaign, and their limited attacking output on the road makes them a genuine risk to suffer a narrow defeat.

Our most confident selections align on a low-scoring affair with Santa Fe emerging victorious. The under 2.5 angle carries sixty percent confidence, and when combined with the BTTS no pick, it paints a picture of a tightly contested match where Santa Fe's defensive organization gives them the edge. We are backing Santa Fe to win with under 2.5 total goals at Estadio El Campín on Wednesday morning.

Our #1 PickUnder 2.5Over/Under Goals@1.55 · 60%
Best ValueSanta FeMatch Result (1X2)@1.89 · 45%
Our Predictions: Santa Fe vs Deportivo Cali — Santa Fe — Win (45%); under 2.5; Both teams to score: No

Frequently Asked Questions

Who will win Santa Fe vs Deportivo Cali?
Our model predicts Santa Fe with 45% confidence based on current form, head-to-head record and statistical analysis.
Is the double chance 1X a good bet for Santa Fe vs Deportivo Cali?
Our double chance pick is 1X with 37% confidence — it covers two outcomes for lower risk.
Who is most likely to score in Santa Fe vs Deportivo Cali?
Hugo Rodallega is our pick to find the net.
What is the Asian Handicap prediction for Santa Fe vs Deportivo Cali?
Our Asian Handicap call is Santa Fe -0.50 with 50% confidence.
How many goals will Santa Fe vs Deportivo Cali have?
We expect Under 2.5 goals (59% confidence), based on both teams scoring and defensive records.
When and where is Santa Fe vs Deportivo Cali played?
Santa Fe vs Deportivo Cali takes place on 23 Sept 2026 at Estadio El Campin.

Additional Information

Santa FeSanta Fe

Top Scorers

C. Mafla
C. MaflaDefender
2Goals
N. Bustos
N. BustosAttacker
1Goals
E. Olivera
E. OliveraDefender
1Goals
F. Fagúndez
F. FagúndezAttacker
1Goals
E. Mosquera
E. MosqueraMidfielder
1Goals

Top Assists

N. Bustos
N. BustosAttacker
2Assists
A. Zapata
A. ZapataMidfielder
1Assists
V. Moreno
V. MorenoDefender
1Assists

Cards

C. Mafla
C. MaflaDefender
20
E. Mosquera
E. MosqueraMidfielder
20
V. Moreno
V. MorenoDefender
20
E. Olivera
E. OliveraDefender
10
F. Fagúndez
F. FagúndezAttacker
10
Deportivo CaliDeportivo Cali

Top Scorers

S. Rodríguez
S. RodríguezAttacker
3Goals
J. Martínez
J. MartínezAttacker
1Goals
A. Hurtado
A. HurtadoAttacker
1Goals
J. Dinenno
J. DinennoAttacker
1Goals
F. Aguilar
F. AguilarDefender
1Goals

Top Assists

J. Martínez
J. MartínezAttacker
3Assists
Y. Quintero
Y. QuinteroMidfielder
1Assists
E. Reynoso
E. ReynosoMidfielder
1Assists
A. Correa
A. CorreaDefender
1Assists

Cards

E. Reynoso
E. ReynosoMidfielder
40
A. Hurtado
A. HurtadoAttacker
20
J. Dinenno
J. DinennoAttacker
20
F. Aguilar
F. AguilarDefender
20
A. Correa
A. CorreaDefender
20

Detailed Form & Recent Matches

Santa Fe
LWWLW
10Played
6Wins
2Draws
2Losses
Points/Game2
Win %60%
Goals/Game2.6
Scored Avg1.6
Conceded Avg1
BTTS60%
Clean Sheets20%
Failed to Score20%

Recent Matches

22 OctWvs Jaguares2-1
18 OctLat Llaneros0-1
6 OctWat Independiente Medellin1-0
29 SeptWat Deportivo Pereira2-1
23 SeptLvs Deportivo Cali0-1
Deportivo Cali
WWDDW
10Played
6Wins
4Draws
0Losses
Points/Game2.2
Win %60%
Goals/Game2
Scored Avg1.6
Conceded Avg0.4
BTTS40%
Clean Sheets60%
Failed to Score20%

Recent Matches

21 OctWat Llaneros3-0
19 OctDvs Junior0-0
10 OctDat Deportivo Pereira0-0
3 OctWvs Alianza Valledupar3-1
28 SeptWvs Águilas Doradas2-0

Head to Head History

Betting Statistics

MetricValue
Total Matches20
Average Goals2.2
BTTS45%
Over 2.5 Goals35%
Over 1.5 Goals70%

Goals by Team

TeamTotalAverage
Santa Fe231.15 per game
Deportivo Cali211.05 per game

Clean Sheets

TeamClean Sheets
Santa Fe7 (35%)
Deportivo Cali5 (25%)
23 Sept 2026Primera ASanta Fe0-1Deportivo Cali
19 Mar 2026Primera ADeportivo Cali1-1Santa Fe
10 Nov 2025Primera ASanta Fe1-0Deportivo Cali
17 May 2025Primera ADeportivo Cali0-2Santa Fe
21 Aug 2024Primera ADeportivo Cali1-3Santa Fe
14 Feb 2024Primera ASanta Fe1-0Deportivo Cali
7 Sept 2023Primera ADeportivo Cali2-2Santa Fe
22 Mar 2023Primera ASanta Fe3-0Deportivo Cali
22 Oct 2022Primera ASanta Fe1-0Deportivo Cali
7 May 2022Primera ADeportivo Cali1-1Santa Fe
18 Jul 2021Primera ASanta Fe1-2Deportivo Cali
1 Mar 2021Primera ADeportivo Cali1-1Santa Fe
20 Oct 2020Primera ADeportivo Cali3-2Santa Fe
24 Nov 2019Primera ASanta Fe1-1Deportivo Cali
14 Nov 2019Primera ADeportivo Cali1-0Santa Fe
12 Oct 2019Primera ADeportivo Cali0-0Santa Fe
21 Apr 2019Primera ASanta Fe1-2Deportivo Cali
29 Sept 2018Primera ASanta Fe0-2Deportivo Cali
1 Apr 2018Primera ADeportivo Cali3-0Santa Fe
19 Aug 2017Primera ASanta Fe2-0Deportivo Cali

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